Publications
- 2022
Gene Therapy in Orthopaedics: Progress and Challenges in Pre-Clinical Development and Translation.
Frontiers in bioengineering and biotechnology. 10. [DOI] 10.3389/fbioe.2022.901317. [PMID] 35837555.
2 citations | PubMed | Publisher's Site - 2018
Gene Therapy for Osteoarthritis: Pharmacokinetics of Intra-Articular Self-Complementary Adeno-Associated Virus Interleukin-1 Receptor Antagonist Delivery in an Equine Model.
Human gene therapy. Clinical development. 29(2):90-100. [DOI] 10.1089/humc.2017.142. [PMID] 29869540.
28 citations | PubMed | Publisher's Site - 2018
Self-Complementary Adeno-Associated Virus-Mediated Interleukin-1 Receptor Antagonist Gene Delivery for the Treatment of Osteoarthritis: Test of Efficacy in an Equine Model.
Human gene therapy. Clinical development. 29(2):101-112. [DOI] 10.1089/humc.2017.143. [PMID] 29869535.
19 citations | PubMed | Publisher's Site - 2013
scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints.
Gene therapy. 20(6):670-7. [DOI] 10.1038/gt.2012.81. [PMID] 23151520.
45 citations | PubMed | Publisher's Site - 2011
Evidence for the osteosarcoma stem cell.
Current orthopaedic practice. 22(4):322-326. [PMID] 21755019.
31 citations | PubMed - 2010
Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo.
Laboratory investigation; a journal of technical methods and pathology. 90(11):1615-27. [DOI] 10.1038/labinvest.2010.145. [PMID] 20697373.
49 citations | PubMed | Publisher's Site - 2009
Chondrogenesis of Bovine Mscs Is Influenced By Adenoviral-Mediated Delivery of Bmp-4, Bmp-7, Indian Hedgehog, and Sox-9
Molecular Therapy. 17. - 2009
Examining the Role of Elevated Blood Glucose in the Severity of Arthrofibrosis Using Intra-Articular Gene Delivery of Tgf-Beta 1
Molecular Therapy. 17. - 2009
Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma.
Cancer research. 69(14):5648-55. [DOI] 10.1158/0008-5472.CAN-08-3580. [PMID] 19584295.
137 citations | PubMed | Publisher's Site - 2009
Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus.
The journal of gene medicine. 11(7):605-14. [DOI] 10.1002/jgm.1334. [PMID] 19384892.
44 citations | PubMed | Publisher's Site - 2008
Perspectives on the use of gene therapy for chronic joint diseases.
Current gene therapy. 8(4):273-86. [PMID] 18691023.
11 citations | PubMed - 2006
Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta.
Arthritis research & therapy. 8(6). [PMID] 17109745.
51 citations | PubMed - 2006
Recruitment of transcription complexes to the beta-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells.
The FEBS journal. 273(4):746-55. [PMID] 16441661.
29 citations | PubMed - 2004
Locus control region elements HS2 and HS3 in combination with chromatin boundaries confer high-level expression of a human beta-globin transgene in a centromeric region.
Genes to cells : devoted to molecular & cellular mechanisms. 9(11):1043-53. [PMID] 15507116.
6 citations | PubMed - 2004
Recruitment of transcription complexes to the beta-globin gene locus in vivo and in vitro.
The Journal of biological chemistry. 279(48):50350-7. [PMID] 15385559.
60 citations | PubMed - 2002
The human beta-globin locus control region.
European journal of biochemistry. 269(6):1589-99. [PMID] 11895428.
110 citations | PubMed - 2001
Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly.
Molecular and cellular biology. 21(8):2629-40. [PMID] 11283243.
48 citations | PubMed
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